Postdoctoral Research @ UCSF
with Dr. Cynthia Kenyon
Longevity Gene Discovery: Transcriptional Analysis of C. elegans Longevity Mutants
PhD in Biochemistry @ Stanford University (1999)
with Dr. James A. Spudich
The Role of Variable Loops & the Conserved Core in Myosin Function: Kinetic Analysis of Dictyostelium Myosin II
BS in Biochemical & Biophysical Sciences, Chemistry minor @ University of Houston (1992)
I am a Professor of Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics at Princeton University. I am also the Director of the Paul F. Glenn Laboratories for Aging Research at Princeton University.
What governs how fast we age? Why do some biological processes stop working earlier than others? And what is happening at the molecular and cellular level as some organisms age while others continue to thrive? Although seemingly philosophical in nature, these questions address one of the major mysteries of biology, the process of aging. With recent developments in genetics, molecular biology, and genomics, we now have the possibility of addressing these questions at the molecular level. Because our ultimate goal is not simply to extend lifespan, but to improve overall health, we must identify the genes associated with biological functions that we typically associate with quality of life. The goal of our laboratory's work is to understand the molecular mechanisms governing longevity and maintenance of the biological processes that exhibit age-related decline.
“Being open to the unexpected.” Mol Biol Cell. (2019) Nov
"Scientist to Watch" spotlight in The Scientist (2006) 20(10):73
"Coleen Murphy: How to stay young at heart, body, and mind" in JCB (2012)