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Found 38 results
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Filters: Keyword is Animals and Author is Murphy, Coleen T  [Clear All Filters]
2003
Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, Li H, Kenyon C.  2003.  Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans.. Nature. 424(6946):277-83.
Hsu A-L, Murphy CT, Kenyon C.  2003.  Regulation of aging and age-related disease by DAF-16 and heat-shock factor.. Science. 300(5622):1142-5.
2004
McCarroll SA, Murphy CT, Zou S, Pletcher SD, Chin C-S, Jan YNung, Kenyon C, Bargmann CI, Li H.  2004.  Comparing genomic expression patterns across species identifies shared transcriptional profile in aging.. Nat Genet. 36(2):197-204.
2006
Kenyon C, Murphy CT.  2006.  Enrichment of regulatory motifs upstream of predicted DAF-16 targets.. Nat Genet. 38(4):397-8;authorreply398.
Murphy CT.  2006.  The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.. Exp Gerontol. 41(10):910-21.
2007
Shaw WM, Luo S, Landis J, Ashraf J, Murphy CT.  2007.  The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling.. Curr Biol. 17(19):1635-45.
Murphy CT, Lee S-J, Kenyon C.  2007.  Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans.. Proc Natl Acad Sci U S A. 104(48):19046-50.
2009
Oliveira RP, Abate JPorter, Dilks K, Landis J, Ashraf J, Murphy CT, T Blackwell K.  2009.  Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf.. Aging Cell. 8(5):524-41.
Chikina MD, Huttenhower C, Murphy CT, Troyanskaya OG.  2009.  Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans.. PLoS Comput Biol. 5(6):e1000417.
Lee S-J, Murphy CT, Kenyon C.  2009.  Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.. Cell Metab. 10(5):379-91.
Luo S, Shaw WM, Ashraf J, Murphy CT.  2009.  TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging.. PLoS Genet. 5(12):e1000789.
2010
Murphy CT.  2010.  Aging: miRacles of longevity? Curr Biol. 20(24):R1076-8.
Kauffman AL, Ashraf JM, M Corces-Zimmerman R, Landis JN, Murphy CT.  2010.  Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age.. PLoS Biol. 8(5):e1000372.
Landis JN, Murphy CT.  2010.  Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO.. Dev Dyn. 239(5):1405-12.
Kaletsky R, Murphy CT.  2010.  The role of insulin/IGF-like signaling in C. elegans longevity and aging.. Dis Model Mech. 3(7-8):415-9.
Luo S, Kleemann GA, Ashraf JM, Shaw WM, Murphy CT.  2010.  TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance.. Cell. 143(2):299-312.
2011
Luo S, Murphy CT.  2011.  Caenorhabditis elegans reproductive aging: Regulation and underlying mechanisms.. Genesis. 49(2):53-65.
Liu G, Rogers J, Murphy CT, Rongo C.  2011.  EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan.. EMBO J. 30(15):2990-3003.
Rizki G, Iwata TNaoko, Li J, Riedel CG, Picard CLafontaine, Jan M, Murphy CT, Lee SSylvia.  2011.  The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO.. PLoS Genet. 7(9):e1002235.
2013
Murphy CT, Hu PJ.  2013.  Insulin/insulin-like growth factor signaling in C. elegans.. WormBook. :1-43.
Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, Bussemaker HJ.  2013.  PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity.. Cell. 154(3):676-690.
2014
Stein GM, Murphy CT.  2014.  C. elegans positive olfactory associative memory is a molecularly conserved behavioral paradigm.. Neurobiol Learn Mem. 115:86-94.
Tepper RG, Murphy CT, Bussemaker HJ.  2014.  DAF-16 and PQM-1: partners in longevity.. Aging (Albany NY). 6(1):5-6.
de Abreu DAndrea Fer, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F et al..  2014.  An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.. PLoS Genet. 10(3):e1004225.
Shi C, Murphy CT.  2014.  Mating induces shrinking and death in Caenorhabditis mothers.. Science. 343(6170):536-40.

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