Publications Search

Found 31 results
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2019
Shi C, Booth LN, Murphy CT.  2019.  Insulin-like peptides and the mTOR-TFEB pathway protect \textitCaenorhabditis elegans hermaphrodites from mating-induced death. eLife. 8:e46413.
2016
Kaletsky R, Lakhina V, Arey R, Williams A, Landis J, Ashraf J, Murphy CT.  2016.  The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators.. Nature. 529(7584):92-6.
2015
Ewald CY, Landis JN, Abate JPorter, Murphy CT, T Blackwell K.  2015.  Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity.. Nature. 519(7541):97-101.
Lakhina V, Murphy CT.  2015.  For longevity, perception is everything.. Cell. 160(5):807-809.
Lakhina V, Arey RN, Kaletsky R, Kauffman A, Stein G, Keyes W, Xu D, Murphy CT.  2015.  Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs.. Neuron. 85(2):330-45.
2014
Stein GM, Murphy CT.  2014.  C. elegans positive olfactory associative memory is a molecularly conserved behavioral paradigm.. Neurobiol Learn Mem. 115:86-94.
Tepper RG, Murphy CT, Bussemaker HJ.  2014.  DAF-16 and PQM-1: partners in longevity.. Aging (Albany NY). 6(1):5-6.
Tepper RG, Murphy CT, Bussemaker HJ.  2014.  DAF-16 and PQM-1: partners in longevity.. Aging (Albany NY). 6(1):5-6.
2013
Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, Bussemaker HJ.  2013.  PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity.. Cell. 154(3):676-690.
Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, Bussemaker HJ.  2013.  PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity.. Cell. 154(3):676-690.
Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, Bussemaker HJ.  2013.  PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity.. Cell. 154(3):676-690.
2011
Rizki G, Iwata TNaoko, Li J, Riedel CG, Picard CLafontaine, Jan M, Murphy CT, Lee SSylvia.  2011.  The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO.. PLoS Genet. 7(9):e1002235.
Rizki G, Iwata TNaoko, Li J, Riedel CG, Picard CLafontaine, Jan M, Murphy CT, Lee SSylvia.  2011.  The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO.. PLoS Genet. 7(9):e1002235.
2010
Landis JN, Murphy CT.  2010.  Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO.. Dev Dyn. 239(5):1405-12.
Luo S, Kleemann GA, Ashraf JM, Shaw WM, Murphy CT.  2010.  TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance.. Cell. 143(2):299-312.
2009
Oliveira RP, Abate JPorter, Dilks K, Landis J, Ashraf J, Murphy CT, T Blackwell K.  2009.  Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf.. Aging Cell. 8(5):524-41.
Oliveira RP, Abate JPorter, Dilks K, Landis J, Ashraf J, Murphy CT, T Blackwell K.  2009.  Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf.. Aging Cell. 8(5):524-41.
Oliveira RP, Abate JPorter, Dilks K, Landis J, Ashraf J, Murphy CT, T Blackwell K.  2009.  Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf.. Aging Cell. 8(5):524-41.
Lee S-J, Murphy CT, Kenyon C.  2009.  Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.. Cell Metab. 10(5):379-91.
Luo S, Shaw WM, Ashraf J, Murphy CT.  2009.  TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging.. PLoS Genet. 5(12):e1000789.
2007
Shaw WM, Luo S, Landis J, Ashraf J, Murphy CT.  2007.  The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling.. Curr Biol. 17(19):1635-45.
Murphy CT, Lee S-J, Kenyon C.  2007.  Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans.. Proc Natl Acad Sci U S A. 104(48):19046-50.
2006
Kenyon C, Murphy CT.  2006.  Enrichment of regulatory motifs upstream of predicted DAF-16 targets.. Nat Genet. 38(4):397-8;authorreply398.
Murphy CT.  2006.  The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.. Exp Gerontol. 41(10):910-21.
Murphy CT.  2006.  The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.. Exp Gerontol. 41(10):910-21.

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