Publications Search

95 Publications

2019

Arey RN, Kaletsky R, Murphy CT. 2019. Nervous system-wide profiling of presynaptic mRNAs reveals regulators of associative memory. Sci Rep, . 9.
Heimbucher T, Murphy CT. 2019. A PBX/MEIS Complex Balances Reproduction and Somatic Resilience. Developmental Cell. 49(2).
Heimbucher T, Murphy C. 2019. Investigating Mechanisms that Control Ubiquitin-Mediated DAF-16/FOXO Protein Turnover. Methods Mol Biol. 1890:41-49. doi:10.1007/978-1-4939-8900-3_4.
Heimbucher T, Hog J, Murphy CT. 2019. PQM-1 controls hypoxic survival via regulation of lipid metabolism. bioRxiv.
Kaletsky R, Moore R, Parsons L, Murphy C. 2019. Cross-kingdom recognition of bacterial small RNAs induces transgenerational pathogenic avoidance. bioRxiv. 697888 .
Kaletsky R, Murphy C. 2019. Gut feelings: microRNAs tune protein quality control and ageing to odours. 1(3): - 307. https://doi.org/10.1038/s42255-019-0042-y.
Lakhina V, McReynolds M, Grimes D, Rabinowitz J, Burdine R, Murphy C. 2019. ZIP-5/bZIP transcription factor regulation of folate metabolism is critical for aging axon regeneration. bioRxiv.:727719. http://biorxiv.org/content/early/2019/08/08/727719.abstract.
Mack HID, Heimbucher T, Murphy CT. 2019. The nematode Caenorhabditis elegans as a model for aging research. Drug Discov Today: Disease Models .
Moore R, Kaletsky R, Murphy C. 2019. Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance. Cell. 177(7): - 1841.e12. https://doi.org/10.1016/j.cell.2019.05.024.
Murphy C. 2019. Being Open to the Unexpected. Mol Biol Cell.
Shi C, Booth L, Murphy C, Kaeberlein M, Wittkopp P, Sutphin G. 2019. Insulin-like peptides and the mTOR-TFEB pathway protect \textitCaenorhabditis elegans hermaphrodites from mating-induced death. eLife. 8:e46413. doi:10.7554/eLife.46413. https://doi.org/10.7554/eLife.46413.

2018

Arey R, Stein G, Kaletsky R, Kauffman A, Murphy C. 2018. Activation of G Signaling Enhances Memory Consolidation and Slows Cognitive Decline. Neuron. 98(3):562-574.e5. doi:10.1016/j.neuron.2018.03.039.
Kaletsky R, Yao V, Williams A, Runnels A, Tadych A, Zhou S, Troyanskaya O, Murphy C. 2018. Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression. PLoS Genet. 14(8):e1007559. doi:10.1371/journal.pgen.1007559.
Moore R, Kaletsky R, Murphy C. 2018. C. elegans pathogenic learning confers multigenerational pathogen avoidance. bioRxiv.. doi:10.1101/476416. https://www.biorxiv.org/content/early/2018/11/21/476416.
Tabuchi T, Rechtsteiner A, Jeffers T, Egelhofer T, Murphy C, Strome S. 2018. Caenorhabditis elegans sperm carry a histone-based epigenetic memory of both spermatogenesis and oogenesis. Nat Commun. 9(1):4310. doi:10.1038/s41467-018-06236-8.
Templeman N, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, Murphy C. 2018. Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity. Curr Biol. 28(5):753-760.e4. doi:10.1016/j.cub.2018.01.052.
Templeman N, Murphy C. 2018. Regulation of reproduction and longevity by nutrient-sensing pathways. The Journal of Cell Biology. 217:93–106. doi:10.1083/jcb.201707168. http://jcb.rupress.org/content/217/1/93.
Yao V, Kaletsky R, Keyes W, Mor D, Wong A, Sohrabi S, Murphy C, Troyanskaya O. 2018. An integrative tissue-network approach to identify and test human disease genes. Nat Biotechnol.. doi:10.1038/nbt.4246.

2017

Arey R, Murphy C. 2017. Conserved regulators of cognitive aging: From worms to humans. Behav Brain Res. 322(Pt B):299-310. doi:10.1016/j.bbr.2016.06.035.
Shi C, Runnels A, Murphy C, Dillin A. 2017. Mating and male pheromone kill \textitCaenorhabditis males through distinct mechanisms. eLife. 6:e23493. doi:10.7554/eLife.23493. https://doi.org/10.7554/eLife.23493.
Son H, Seo M, Ham S, Hwang W, Lee D, An S, Artan M, Seo K, Kaletsky R, Arey R, et al. 2017. RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans. Nat Commun. 8:14749. doi:10.1038/ncomms14749.

2016

Crocker A, Guan X-J, Murphy C, Murthy M. 2016. Cell-Type-Specific Transcriptome Analysis in the Drosophila Mushroom Body Reveals Memory-Related Changes in Gene Expression. Cell Rep. 15(7):1580-1596. doi:10.1016/j.celrep.2016.04.046.
Kaletsky R, Lakhina V, Arey R, Williams A, Landis J, Ashraf J, Murphy C. 2016. The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators. Nature. 529(7584):92-6. doi:10.1038/nature16483.
Li L-B, Lei H, Arey R, Li P, Liu J, Murphy C, Xu X, Shen K. 2016. The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory. Curr Biol. 26(5):605-15. doi:10.1016/j.cub.2015.12.068.
Maliha G, Murphy C. 2016. A simple offspring-to-mother size ratio predicts post-reproductive lifespan. bioRxiv.. doi:10.1101/048835. https://www.biorxiv.org/content/early/2016/04/15/048835.