Publications Search

Found 53 results
Author Keyword Title [ Type(Desc)] Year
Filters: Author is Murphy, Coleen T  [Clear All Filters]
Journal Article
Lakhina V, Arey RN, Kaletsky R, Kauffman A, Stein G, Keyes W, Xu D, Murphy CT.  2015.  Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs.. Neuron. 85(2):330-45.
Chikina MD, Huttenhower C, Murphy CT, Troyanskaya OG.  2009.  Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans.. PLoS Comput Biol. 5(6):e1000417.
Lee S-J, Murphy CT, Kenyon C.  2009.  Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.. Cell Metab. 10(5):379-91.
Kauffman AL, Ashraf JM, M Corces-Zimmerman R, Landis JN, Murphy CT.  2010.  Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age.. PLoS Biol. 8(5):e1000372.
Templeman NM, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, Murphy CT.  2018.  Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity.. Curr Biol. 28(5):753-760.e4.
Murphy CT, Hu PJ.  2013.  Insulin/insulin-like growth factor signaling in C. elegans.. WormBook. :1-43.
Shi C, Booth LN, Murphy CT.  2019.  Insulin-like peptides and the mTOR-TFEB pathway protect \textitCaenorhabditis elegans hermaphrodites from mating-induced death. eLife. 8:e46413.
de Abreu DAndrea Fer, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F et al..  2014.  An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.. PLoS Genet. 10(3):e1004225.
Landis JN, Murphy CT.  2010.  Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO.. Dev Dyn. 239(5):1405-12.
Yao V, Kaletsky R, Keyes W, Mor DE, Wong AK, Sohrabi S, Murphy CT, Troyanskaya OG.  2018.  An integrative tissue-network approach to identify and test human disease genes.. Nat Biotechnol.
Stein GM, Murphy CT.  2012.  The Intersection of Aging, Longevity Pathways, and Learning and Memory in C. elegans.. Front Genet. 3:259.
Heimbucher T, Murphy CT.  2019.  Investigating Mechanisms that Control Ubiquitin-Mediated DAF-16/FOXO Protein Turnover.. Methods Mol Biol. 1890:41-49.
Shi C, Runnels AM, Murphy CT.  2017.  Mating and male pheromone kill \textitCaenorhabditis males through distinct mechanisms. eLife. 6:e23493.
Shi C, Murphy CT.  2014.  Mating induces shrinking and death in Caenorhabditis mothers.. Science. 343(6170):536-40.
Shi C, Runnels AM, Murphy CT.  2016.  Mating-induced Male Death and Pheromone Toxin-regulated Androstasis. bioRxiv.
Li S, Stone HA, Murphy CT.  2015.  A microfluidic device and automatic counting system for the study of C. elegans reproductive aging.. Lab Chip. 15(2):524-31.
Li L-B, Lei H, Arey RN, Li P, Liu J, Murphy CT, Xu XZShawn, Shen K.  2016.  The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory.. Curr Biol. 26(5):605-15.
Caudy AA, Guan Y, Jia Y, Hansen C, DeSevo C, Hayes AP, Agee J, Alvarez-Dominguez JR, Arellano H, Barrett D et al..  2013.  A new system for comparative functional genomics of Saccharomyces yeasts.. Genetics. 195(1):275-87.
Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, Bussemaker HJ.  2013.  PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity.. Cell. 154(3):676-690.
Hsu A-L, Murphy CT, Kenyon C.  2003.  Regulation of aging and age-related disease by DAF-16 and heat-shock factor.. Science. 300(5622):1142-5.
Son HG, Seo M, Ham S, Hwang W, Lee D, An SWoo A, Artan M, Seo K, Kaletsky R, Arey RN et al..  2017.  RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans.. Nat Commun. 8:14749.
Kaletsky R, Murphy CT.  2010.  The role of insulin/IGF-like signaling in C. elegans longevity and aging.. Dis Model Mech. 3(7-8):415-9.
Murphy CT.  2006.  The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.. Exp Gerontol. 41(10):910-21.
Maliha G, Murphy CT.  2016.  A simple offspring-to-mother size ratio predicts post-reproductive lifespan. bioRxiv.
Luo S, Shaw WM, Ashraf J, Murphy CT.  2009.  TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging.. PLoS Genet. 5(12):e1000789.

Pages