Publications Search

Found 95 results
Author Keyword Title [ Type(Asc)] Year
Journal Article
Shi C, Runnels AM, Murphy CT.  2016.  Mating-induced Male Death and Pheromone Toxin-regulated Androstasis. bioRxiv.
Shi C, Murphy CT.  2014.  Mating induces shrinking and death in Caenorhabditis mothers.. Science. 343(6170):536-40.
Shi C, Runnels AM, Murphy CT.  2017.  Mating and male pheromone kill \textitCaenorhabditis males through distinct mechanisms. eLife. 6:e23493.
Heimbucher T, Murphy CT.  2019.  Investigating Mechanisms that Control Ubiquitin-Mediated DAF-16/FOXO Protein Turnover.. Methods Mol Biol. 1890:41-49.
Stein GM, Murphy CT.  2012.  The Intersection of Aging, Longevity Pathways, and Learning and Memory in C. elegans.. Front Genet. 3:259.
Yao V, Kaletsky R, Keyes W, Mor DE, Wong AK, Sohrabi S, Murphy CT, Troyanskaya OG.  2018.  An integrative tissue-network approach to identify and test human disease genes.. Nat Biotechnol.
Landis JN, Murphy CT.  2010.  Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO.. Dev Dyn. 239(5):1405-12.
de Abreu DAndrea Fer, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F et al..  2014.  An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.. PLoS Genet. 10(3):e1004225.
Shi C, Booth LN, Murphy CT.  2019.  Insulin-like peptides and the mTOR-TFEB pathway protect \textitCaenorhabditis elegans hermaphrodites from mating-induced death. eLife. 8:e46413.
Murphy CT, Hu PJ.  2013.  Insulin/insulin-like growth factor signaling in C. elegans.. WormBook. :1-43.
Templeman NM, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, Murphy CT.  2018.  Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity.. Curr Biol. 28(5):753-760.e4.
Kauffman AL, Ashraf JM, M Corces-Zimmerman R, Landis JN, Murphy CT.  2010.  Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age.. PLoS Biol. 8(5):e1000372.
Kaletsky R, Murphy CT.  2019.  Gut feelings: microRNAs tune protein quality control and ageing to odours. 1(3):-307.
Lee S-J, Murphy CT, Kenyon C.  2009.  Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.. Cell Metab. 10(5):379-91.
Chikina MD, Huttenhower C, Murphy CT, Troyanskaya OG.  2009.  Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans.. PLoS Comput Biol. 5(6):e1000417.
Lakhina V, Arey RN, Kaletsky R, Kauffman A, Stein G, Keyes W, Xu D, Murphy CT.  2015.  Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs.. Neuron. 85(2):330-45.
Lakhina V, Murphy CT.  2015.  Genome Sequencing Fishes out Longevity Genes.. Cell. 163(6):1312-3.
Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, Li H, Kenyon C.  2003.  Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans.. Nature. 424(6946):277-83.
Lakhina V, Murphy CT.  2015.  For longevity, perception is everything.. Cell. 160(5):807-809.
Shi C, Murphy CT.  2016.  Feeding the germline.. Genes Dev. 30(3):249-50.
Rizki G, Iwata TNaoko, Li J, Riedel CG, Picard CLafontaine, Jan M, Murphy CT, Lee SSylvia.  2011.  The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO.. PLoS Genet. 7(9):e1002235.
Kenyon C, Murphy CT.  2006.  Enrichment of regulatory motifs upstream of predicted DAF-16 targets.. Nat Genet. 38(4):397-8;authorreply398.
Kleemann GA, Murphy CT.  2009.  The endocrine regulation of aging in Caenorhabditis elegans.. Mol Cell Endocrinol. 299(1):51-7.
Liu G, Rogers J, Murphy CT, Rongo C.  2011.  EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan.. EMBO J. 30(15):2990-3003.
Murphy CT, Spudich JA.  1998.  Dictyostelium myosin 25-50K loop substitutions specifically affect ADP release rates.. Biochemistry. 37(19):6738-44.