Publications Search

95 Publications

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Kaletsky R, Murphy C. 2010. The role of insulin/IGF-like signaling in C. elegans longevity and aging. Dis Model Mech. 3(7-8):415-9. doi:10.1242/dmm.001040.
Kaletsky R, Murphy C. 2019. Gut feelings: microRNAs tune protein quality control and ageing to odours. 1(3): - 307. https://doi.org/10.1038/s42255-019-0042-y.
Kaletsky R, Moore R, Parsons L, Murphy C. 2019. Cross-kingdom recognition of bacterial small RNAs induces transgenerational pathogenic avoidance. bioRxiv. 697888 .
Kaletsky R, Yao V, Williams A, Runnels A, Tadych A, Zhou S, Troyanskaya O, Murphy C. 2018. Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression. PLoS Genet. 14(8):e1007559. doi:10.1371/journal.pgen.1007559.
Kauffman A, Ashraf J, Corces-Zimmerman R, Landis J, Murphy C. 2010. Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age. PLoS Biol. 8(5):e1000372. doi:10.1371/journal.pbio.1000372.
Kauffman A, Parsons L, Stein G, Wills A, Kaletsky R, Murphy C. 2011. C. elegans positive butanone learning, short-term, and long-term associative memory assays. J Vis Exp.(49). doi:10.3791/2490.
Kenyon C, Murphy C. 2006. Enrichment of regulatory motifs upstream of predicted DAF-16 targets. Nat Genet. 38(4):397-8; author reply 398. doi:10.1038/ng0406-397.
Kleemann G, Murphy C. 2009. The endocrine regulation of aging in Caenorhabditis elegans. Mol Cell Endocrinol. 299(1):51-7. doi:10.1016/j.mce.2008.10.048.

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Lakhina V, Arey R, Kaletsky R, Kauffman A, Stein G, Keyes W, Xu D, Murphy C. 2015. Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs. Neuron. 85(2):330-45. doi:10.1016/j.neuron.2014.12.029.
Lakhina V, Murphy C. 2015. For longevity, perception is everything. Cell. 160(5):807-809. doi:10.1016/j.cell.2015.02.027.
Lakhina V, Murphy C. 2015. Genome Sequencing Fishes out Longevity Genes. Cell. 163(6):1312-3. doi:10.1016/j.cell.2015.11.040.
Lakhina V, McReynolds M, Grimes D, Rabinowitz J, Burdine R, Murphy C. 2019. ZIP-5/bZIP transcription factor regulation of folate metabolism is critical for aging axon regeneration. bioRxiv.:727719. http://biorxiv.org/content/early/2019/08/08/727719.abstract.
Landis J, Murphy C. 2010. Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO. Dev Dyn. 239(5):1405-12. doi:10.1002/dvdy.22244.
Lee S-J, Murphy C, Kenyon C. 2009. Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression. Cell Metab. 10(5):379-91. doi:10.1016/j.cmet.2009.10.003.
Lee Y, Jung Y, Jeong DE, Hwang W, Ham S, Park HH, Kwon S, Ashraf JM, Murphy CT, Lee SV. 2021. 9. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop.
Li S, Stone H, Murphy C. 2015. A microfluidic device and automatic counting system for the study of C. elegans reproductive aging. Lab Chip. 15(2):524-31. doi:10.1039/c4lc01028k.
Li L-B, Lei H, Arey R, Li P, Liu J, Murphy C, Xu X, Shen K. 2016. The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory. Curr Biol. 26(5):605-15. doi:10.1016/j.cub.2015.12.068.
Liu G, Rogers J, Murphy C, Rongo C. 2011. EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan. EMBO J. 30(15):2990-3003. doi:10.1038/emboj.2011.195.
Luo S, Shaw W, Ashraf J, Murphy C. 2009. TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging. PLoS Genet. 5(12):e1000789. doi:10.1371/journal.pgen.1000789.
Luo S, Kleemann G, Ashraf J, Shaw W, Murphy C. 2010. TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance. Cell. 143(2):299-312. doi:10.1016/j.cell.2010.09.013.
Luo S, Murphy C. 2011. Caenorhabditis elegans reproductive aging: Regulation and underlying mechanisms. Genesis. 49(2):53-65. doi:10.1002/dvg.20694.

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Mack HID, Heimbucher T, Murphy CT. 2019. The nematode Caenorhabditis elegans as a model for aging research. Drug Discov Today: Disease Models .
Maliha G, Murphy C. 2016. A simple offspring-to-mother size ratio predicts post-reproductive lifespan. bioRxiv.. doi:10.1101/048835. https://www.biorxiv.org/content/early/2016/04/15/048835.
McCarroll S, Murphy C, Zou S, Pletcher S, Chin C-S, Jan Y, Kenyon C, Bargmann C, Li H. 2004. Comparing genomic expression patterns across species identifies shared transcriptional profile in aging. Nat Genet. 36(2):197-204. doi:10.1038/ng1291.
Moore RS, Kaletsky R, Lesnik C, Cota V, Blackman E, Parsons LR, Gitai Z, Murphy CT. 2020. 1. “Horizontal and vertical transmission of transgenerational memories via the Cer1 transposon. bioRxiv. https://doi.org/10.1101/2020.12.28.424563 .