Publications Search

95 Publications

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Kaletsky R, Murphy CT. 2020. 8. Transcriptional Profiling of C. elegans Adult Cells and Tissues with Age. .Methods Mol Biol. https://pubmed.ncbi.nlm.nih.gov/32410035/.
Kaletsky R, Moore RS, Vrla GD, Parsons LR, Gitai Z, Murphy CT. 2020. 9d. C. elegans “read” bacterial non-coding RNA to learn pathogenic avoidance. bioRxiv .
Kaletsky R, Lakhina V, Arey R, Williams A, Landis J, Ashraf J, Murphy C. 2016. The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators. Nature. 529(7584):92-6. doi:10.1038/nature16483.
Kaletsky R, Moore RS, Vrla GD, Parsons LR, Gitai Z, Murphy CT. 2020. 5. C. elegans interprets bacterial non-coding RNAs to learn pathogenic avoidance. Nature.
Kauffman A, Ashraf J, Corces-Zimmerman R, Landis J, Murphy C. 2010. Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age. PLoS Biol. 8(5):e1000372. doi:10.1371/journal.pbio.1000372.
Kauffman A, Parsons L, Stein G, Wills A, Kaletsky R, Murphy C. 2011. C. elegans positive butanone learning, short-term, and long-term associative memory assays. J Vis Exp.(49). doi:10.3791/2490.
Kenyon C, Murphy C. 2006. Enrichment of regulatory motifs upstream of predicted DAF-16 targets. Nat Genet. 38(4):397-8; author reply 398. doi:10.1038/ng0406-397.
Kleemann G, Murphy C. 2009. The endocrine regulation of aging in Caenorhabditis elegans. Mol Cell Endocrinol. 299(1):51-7. doi:10.1016/j.mce.2008.10.048.

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Lakhina V, McReynolds M, Grimes D, Rabinowitz J, Burdine R, Murphy C. 2019. ZIP-5/bZIP transcription factor regulation of folate metabolism is critical for aging axon regeneration. bioRxiv.:727719. http://biorxiv.org/content/early/2019/08/08/727719.abstract.
Lakhina V, Arey R, Kaletsky R, Kauffman A, Stein G, Keyes W, Xu D, Murphy C. 2015. Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs. Neuron. 85(2):330-45. doi:10.1016/j.neuron.2014.12.029.
Lakhina V, Murphy C. 2015. For longevity, perception is everything. Cell. 160(5):807-809. doi:10.1016/j.cell.2015.02.027.
Lakhina V, Murphy C. 2015. Genome Sequencing Fishes out Longevity Genes. Cell. 163(6):1312-3. doi:10.1016/j.cell.2015.11.040.
Landis J, Murphy C. 2010. Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO. Dev Dyn. 239(5):1405-12. doi:10.1002/dvdy.22244.
Lee Y, Jung Y, Jeong DE, Hwang W, Ham S, Park HH, Kwon S, Ashraf JM, Murphy CT, Lee SV. 2021. 9. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop.
Lee S-J, Murphy C, Kenyon C. 2009. Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression. Cell Metab. 10(5):379-91. doi:10.1016/j.cmet.2009.10.003.
Li S, Stone H, Murphy C. 2015. A microfluidic device and automatic counting system for the study of C. elegans reproductive aging. Lab Chip. 15(2):524-31. doi:10.1039/c4lc01028k.
Li L-B, Lei H, Arey R, Li P, Liu J, Murphy C, Xu X, Shen K. 2016. The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory. Curr Biol. 26(5):605-15. doi:10.1016/j.cub.2015.12.068.
Liu G, Rogers J, Murphy C, Rongo C. 2011. EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan. EMBO J. 30(15):2990-3003. doi:10.1038/emboj.2011.195.
Luo S, Kleemann G, Ashraf J, Shaw W, Murphy C. 2010. TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance. Cell. 143(2):299-312. doi:10.1016/j.cell.2010.09.013.
Luo S, Murphy C. 2011. Caenorhabditis elegans reproductive aging: Regulation and underlying mechanisms. Genesis. 49(2):53-65. doi:10.1002/dvg.20694.
Luo S, Shaw W, Ashraf J, Murphy C. 2009. TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging. PLoS Genet. 5(12):e1000789. doi:10.1371/journal.pgen.1000789.

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Mack HID, Heimbucher T, Murphy CT. 2019. The nematode Caenorhabditis elegans as a model for aging research. Drug Discov Today: Disease Models .
Maliha G, Murphy C. 2016. A simple offspring-to-mother size ratio predicts post-reproductive lifespan. bioRxiv.. doi:10.1101/048835. https://www.biorxiv.org/content/early/2016/04/15/048835.
McCarroll S, Murphy C, Zou S, Pletcher S, Chin C-S, Jan Y, Kenyon C, Bargmann C, Li H. 2004. Comparing genomic expression patterns across species identifies shared transcriptional profile in aging. Nat Genet. 36(2):197-204. doi:10.1038/ng1291.
Moore RS, Kaletsky R, Lesnik C, Cota V, Blackman E, Parsons LR, Gitai Z, Murphy CT. 2021. 5. The role of the Cer1 transposon in horizontal transfer of transgenerational memory. Cell.