Publications Search

95 Publications

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Moore R, Kaletsky R, Murphy C. 2019. Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance. Cell. 177(7): - 1841.e12. https://doi.org/10.1016/j.cell.2019.05.024.
Moore RS, Kaletsky R, Lesnik C, Cota V, Blackman E, Parsons LR, Gitai Z, Murphy CT. 2020. 1. “Horizontal and vertical transmission of transgenerational memories via the Cer1 transposon. bioRxiv. https://doi.org/10.1101/2020.12.28.424563 .
Moore R, Kaletsky R, Murphy C. 2018. C. elegans pathogenic learning confers multigenerational pathogen avoidance. bioRxiv.. doi:10.1101/476416. https://www.biorxiv.org/content/early/2018/11/21/476416.
Moore RS, Kaletsky R, Murphy CT. 2021. 7. Protocol for transgenerational learned pathogen avoidance behavior assays in Caenorhabditis elegans. STAR protocols.
Mor DE, Huertas F, Morse AM, Kaletsky R, Murphy CT, Kalia V, Miller GW, Moskalenko O, Conesa A, McIntyre LM. 2021. 4. GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease. bioRxiv.
Mor DE, Sohrabi S, Kaletsky R, Keyes W, Kalia V, Miller GW, Murphy CT. 2020. 9b. Metabolic defects cause hyperactive mitochondria and Parkinson’s disease-like traits. bioRxiv.
Mor DE, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, Miller GW, Murphy CT. 2020. 4. Metformin rescues Parkinson’s disease phenotypes caused by hyperactive mitochondria. Proc Natl Acad Sci U S A.
Murphy C. 2006. Using whole-genome transcriptional analyses to identify molecular mechanisms of aging. Drug Discovery Today: Disease Mechanisms. 3:41 - 46. doi:https://doi.org/10.1016/j.ddmec.2006.02.012. http://www.sciencedirect.com/science/article/pii/S1740676506000125.
Murphy C. 2010. Aging: miRacles of longevity?. Curr Biol. 20(24):R1076-8. doi:10.1016/j.cub.2010.11.018.
Murphy C, Hu P. 2013. Insulin/insulin-like growth factor signaling in C. elegans. WormBook.:1-43. doi:10.1895/wormbook.1.164.1.
Murphy C. 2019. Being Open to the Unexpected. Mol Biol Cell.
Murphy C, Spudich J. 1998. Dictyostelium myosin 25-50K loop substitutions specifically affect ADP release rates. Biochemistry. 37(19):6738-44. doi:10.1021/bi972903j.
Murphy C, Spudich J. 1999. The sequence of the myosin 50-20K loop affects Myosin's affinity for actin throughout the actin-myosin ATPase cycle and its maximum ATPase activity. Biochemistry. 38(12):3785-92. doi:10.1021/bi9826815.
Murphy CT. 2020. 9c. Short and sweet. Elife. https://elifesciences.org/articles/55220.
Murphy C, Spudich J. 2000. Variable surface loops and myosin activity: accessories to a motor. J Muscle Res Cell Motil. 21(2):139-51.
Murphy C, Rock R, Spudich J. 2001. A myosin II mutation uncouples ATPase activity from motility and shortens step size. Nat Cell Biol. 3(3):311-5. doi:10.1038/35060110.
Murphy C, McCarroll S, Bargmann C, Fraser A, Kamath R, Ahringer J, Li H, Kenyon C. 2003. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature. 424(6946):277-83. doi:10.1038/nature01789.
Murphy C. 2006. The search for DAF-16/FOXO transcriptional targets: approaches and discoveries. Exp Gerontol. 41(10):910-21. doi:10.1016/j.exger.2006.06.040.
Murphy C, Lee S-J, Kenyon C. 2007. Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans. Proc Natl Acad Sci U S A. 104(48):19046-50. doi:10.1073/pnas.0709613104.

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Oliveira R, Abate J, Dilks K, Landis J, Ashraf J, Murphy C, Blackwell K. 2009. Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf. Aging Cell. 8(5):524-41. doi:10.1111/j.1474-9726.2009.00501.x.

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Rahimi M, Sohrabi S, Murphy C. 2022. 1. Novel elasticity measurements reveal C. elegans cuticle stiffens with age and in a long-lived mutant. Biophysical Society.
Rizki G, Iwata T, Li J, Riedel C, Picard C, Jan M, Murphy C, Lee S. 2011. The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO. PLoS Genet. 7(9):e1002235. doi:10.1371/journal.pgen.1002235.

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Shaw W, Luo S, Landis J, Ashraf J, Murphy C. 2007. The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling. Curr Biol. 17(19):1635-45. doi:10.1016/j.cub.2007.08.058.
Shi C, Runnels A, Murphy C. 2016. Mating-induced Male Death and Pheromone Toxin-regulated Androstasis. bioRxiv.. doi:10.1101/034181. https://www.biorxiv.org/content/early/2016/11/22/034181.
Shi C, Murphy CT. 2021. 3. piRNAs regulate a Hedgehog germline-to-soma pro-aging signal. bioRxiv .