Publications Search

95 Publications

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Moore R, Kaletsky R, Murphy C. 2018. C. elegans pathogenic learning confers multigenerational pathogen avoidance. bioRxiv.. doi:10.1101/476416. https://www.biorxiv.org/content/early/2018/11/21/476416.
Moore RS, Kaletsky R, Murphy CT. 2021. 7. Protocol for transgenerational learned pathogen avoidance behavior assays in Caenorhabditis elegans. STAR protocols.
Moore RS, Kaletsky R, Lesnik C, Cota V, Blackman E, Parsons LR, Gitai Z, Murphy CT. 2021. 5. The role of the Cer1 transposon in horizontal transfer of transgenerational memory. Cell.
Moore R, Kaletsky R, Murphy C. 2019. Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance. Cell. 177(7): - 1841.e12. https://doi.org/10.1016/j.cell.2019.05.024.
Mor DE, Sohrabi S, Kaletsky R, Keyes W, Kalia V, Miller GW, Murphy CT. 2020. 9b. Metabolic defects cause hyperactive mitochondria and Parkinson’s disease-like traits. bioRxiv.
Mor DE, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, Miller GW, Murphy CT. 2020. 4. Metformin rescues Parkinson’s disease phenotypes caused by hyperactive mitochondria. Proc Natl Acad Sci U S A.
Mor DE, Huertas F, Morse AM, Kaletsky R, Murphy CT, Kalia V, Miller GW, Moskalenko O, Conesa A, McIntyre LM. 2021. 4. GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease. bioRxiv.
Murphy C, Spudich J. 1999. The sequence of the myosin 50-20K loop affects Myosin's affinity for actin throughout the actin-myosin ATPase cycle and its maximum ATPase activity. Biochemistry. 38(12):3785-92. doi:10.1021/bi9826815.
Murphy CT. 2020. 9c. Short and sweet. Elife. https://elifesciences.org/articles/55220.
Murphy C, Spudich J. 2000. Variable surface loops and myosin activity: accessories to a motor. J Muscle Res Cell Motil. 21(2):139-51.
Murphy C, Rock R, Spudich J. 2001. A myosin II mutation uncouples ATPase activity from motility and shortens step size. Nat Cell Biol. 3(3):311-5. doi:10.1038/35060110.
Murphy C, McCarroll S, Bargmann C, Fraser A, Kamath R, Ahringer J, Li H, Kenyon C. 2003. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature. 424(6946):277-83. doi:10.1038/nature01789.
Murphy C. 2006. The search for DAF-16/FOXO transcriptional targets: approaches and discoveries. Exp Gerontol. 41(10):910-21. doi:10.1016/j.exger.2006.06.040.
Murphy C, Lee S-J, Kenyon C. 2007. Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans. Proc Natl Acad Sci U S A. 104(48):19046-50. doi:10.1073/pnas.0709613104.
Murphy C. 2006. Using whole-genome transcriptional analyses to identify molecular mechanisms of aging. Drug Discovery Today: Disease Mechanisms. 3:41 - 46. doi:https://doi.org/10.1016/j.ddmec.2006.02.012. http://www.sciencedirect.com/science/article/pii/S1740676506000125.
Murphy C. 2010. Aging: miRacles of longevity?. Curr Biol. 20(24):R1076-8. doi:10.1016/j.cub.2010.11.018.
Murphy C, Hu P. 2013. Insulin/insulin-like growth factor signaling in C. elegans. WormBook.:1-43. doi:10.1895/wormbook.1.164.1.
Murphy C. 2019. Being Open to the Unexpected. Mol Biol Cell.
Murphy C, Spudich J. 1998. Dictyostelium myosin 25-50K loop substitutions specifically affect ADP release rates. Biochemistry. 37(19):6738-44. doi:10.1021/bi972903j.

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Oliveira R, Abate J, Dilks K, Landis J, Ashraf J, Murphy C, Blackwell K. 2009. Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf. Aging Cell. 8(5):524-41. doi:10.1111/j.1474-9726.2009.00501.x.

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Rahimi M, Sohrabi S, Murphy C. 2022. 1. Novel elasticity measurements reveal C. elegans cuticle stiffens with age and in a long-lived mutant. Biophysical Society.
Rizki G, Iwata T, Li J, Riedel C, Picard C, Jan M, Murphy C, Lee S. 2011. The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO. PLoS Genet. 7(9):e1002235. doi:10.1371/journal.pgen.1002235.

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Shaw W, Luo S, Landis J, Ashraf J, Murphy C. 2007. The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling. Curr Biol. 17(19):1635-45. doi:10.1016/j.cub.2007.08.058.
Shi C, Murphy CT. 2020. 3. Sex and Death. Curr. Topics in Dev. Biol.
Shi C, Murphy C. 2016. Feeding the germline. Genes Dev. 30(3):249-50. doi:10.1101/gad.276980.115.