Publications Search

95 Publications


Shi C, Murphy C. 2016. Feeding the germline. Genes Dev. 30(3):249-50. doi:10.1101/gad.276980.115.
Shi C, Runnels A, Murphy C. 2016. Mating-induced Male Death and Pheromone Toxin-regulated Androstasis. bioRxiv.. doi:10.1101/034181.


DiLoreto R, Murphy C. 2015. The cell biology of aging. Mol Biol Cell. 26(25):4524-31. doi:10.1091/mbc.E14-06-1084.
Ewald C, Landis J, Abate J, Murphy C, Blackwell K. 2015. Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity. Nature. 519(7541):97-101. doi:10.1038/nature14021.
Hahm J-H, Kim S, DiLoreto R, Shi C, Lee S-J, Murphy C, Nam H. 2015. C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation. Nat Commun. 6:8919. doi:10.1038/ncomms9919.
Lakhina V, Murphy C. 2015. Genome Sequencing Fishes out Longevity Genes. Cell. 163(6):1312-3. doi:10.1016/j.cell.2015.11.040.
Lakhina V, Arey R, Kaletsky R, Kauffman A, Stein G, Keyes W, Xu D, Murphy C. 2015. Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs. Neuron. 85(2):330-45. doi:10.1016/j.neuron.2014.12.029.
Lakhina V, Murphy C. 2015. For longevity, perception is everything. Cell. 160(5):807-809. doi:10.1016/j.cell.2015.02.027.
Li S, Stone H, Murphy C. 2015. A microfluidic device and automatic counting system for the study of C. elegans reproductive aging. Lab Chip. 15(2):524-31. doi:10.1039/c4lc01028k.
Wang J, Kaletsky R, Silva M, Williams A, Haas L, Androwski R, Landis J, Patrick C, Rashid A, Santiago-Martinez D, et al. 2015. Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis. Curr Biol. 25(24):3232-8. doi:10.1016/j.cub.2015.10.057.


de Abreu D, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes W, Nash Z, López-Moyado I, Vaggi F, et al. 2014. An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology. PLoS Genet. 10(3):e1004225. doi:10.1371/journal.pgen.1004225.
Shi C, Murphy C. 2014. Mating induces shrinking and death in Caenorhabditis mothers. Science. 343(6170):536-40. doi:10.1126/science.1242958.
Stein G, Murphy C. 2014. C. elegans positive olfactory associative memory is a molecularly conserved behavioral paradigm. Neurobiol Learn Mem. 115:86-94. doi:10.1016/j.nlm.2014.07.011.
Tepper R, Murphy C, Bussemaker H. 2014. DAF-16 and PQM-1: partners in longevity. Aging (Albany NY). 6(1):5-6. doi:10.18632/aging.100628.


Caudy A, Guan Y, Jia Y, Hansen C, DeSevo C, Hayes A, Agee J, Alvarez-Dominguez J, Arellano H, Barrett D, et al. 2013. A new system for comparative functional genomics of Saccharomyces yeasts. Genetics. 195(1):275-87. doi:10.1534/genetics.113.152918.
Murphy C, Hu P. 2013. Insulin/insulin-like growth factor signaling in C. elegans. WormBook.:1-43. doi:10.1895/wormbook.1.164.1.
Tepper R, Ashraf J, Kaletsky R, Kleemann G, Murphy C, Bussemaker H. 2013. PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity. Cell. 154(3):676-690. doi:10.1016/j.cell.2013.07.006.


Blackstone C, Murphy C. 2012. Cell biology of disease and aging: a two-way street. Molecular Biology of the Cell. 23:975-975. doi:10.1091/mbc.e11-12-0985.
Stein G, Murphy C. 2012. The Intersection of Aging, Longevity Pathways, and Learning and Memory in C. elegans. Front Genet. 3:259. doi:10.3389/fgene.2012.00259.


Kauffman A, Parsons L, Stein G, Wills A, Kaletsky R, Murphy C. 2011. C. elegans positive butanone learning, short-term, and long-term associative memory assays. J Vis Exp.(49). doi:10.3791/2490.
Liu G, Rogers J, Murphy C, Rongo C. 2011. EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan. EMBO J. 30(15):2990-3003. doi:10.1038/emboj.2011.195.
Luo S, Murphy C. 2011. Caenorhabditis elegans reproductive aging: Regulation and underlying mechanisms. Genesis. 49(2):53-65. doi:10.1002/dvg.20694.
Rizki G, Iwata T, Li J, Riedel C, Picard C, Jan M, Murphy C, Lee S. 2011. The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO. PLoS Genet. 7(9):e1002235. doi:10.1371/journal.pgen.1002235.


Kaletsky R, Murphy C. 2010. The role of insulin/IGF-like signaling in C. elegans longevity and aging. Dis Model Mech. 3(7-8):415-9. doi:10.1242/dmm.001040.
Kauffman A, Ashraf J, Corces-Zimmerman R, Landis J, Murphy C. 2010. Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age. PLoS Biol. 8(5):e1000372. doi:10.1371/journal.pbio.1000372.