Publications Search

Found 94 results
Author Keyword Title [ Type(Desc)] Year
Journal Article
Lakhina V, Murphy CT.  2015.  For longevity, perception is everything.. Cell. 160(5):807-809.
Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, Li H, Kenyon C.  2003.  Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans.. Nature. 424(6946):277-83.
Lakhina V, Murphy CT.  2015.  Genome Sequencing Fishes out Longevity Genes.. Cell. 163(6):1312-3.
Lakhina V, Arey RN, Kaletsky R, Kauffman A, Stein G, Keyes W, Xu D, Murphy CT.  2015.  Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs.. Neuron. 85(2):330-45.
Chikina MD, Huttenhower C, Murphy CT, Troyanskaya OG.  2009.  Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans.. PLoS Comput Biol. 5(6):e1000417.
Lee S-J, Murphy CT, Kenyon C.  2009.  Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.. Cell Metab. 10(5):379-91.
Kaletsky R, Murphy CT.  2019.  Gut feelings: microRNAs tune protein quality control and ageing to odours. 1(3):-307.
Kauffman AL, Ashraf JM, M Corces-Zimmerman R, Landis JN, Murphy CT.  2010.  Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age.. PLoS Biol. 8(5):e1000372.
Templeman NM, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, Murphy CT.  2018.  Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity.. Curr Biol. 28(5):753-760.e4.
Murphy CT, Hu PJ.  2013.  Insulin/insulin-like growth factor signaling in C. elegans.. WormBook. :1-43.
Shi C, Booth LN, Murphy CT.  2019.  Insulin-like peptides and the mTOR-TFEB pathway protect \textitCaenorhabditis elegans hermaphrodites from mating-induced death. eLife. 8:e46413.
de Abreu DAndrea Fer, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F et al..  2014.  An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.. PLoS Genet. 10(3):e1004225.
Landis JN, Murphy CT.  2010.  Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO.. Dev Dyn. 239(5):1405-12.
Yao V, Kaletsky R, Keyes W, Mor DE, Wong AK, Sohrabi S, Murphy CT, Troyanskaya OG.  2018.  An integrative tissue-network approach to identify and test human disease genes.. Nat Biotechnol.
Stein GM, Murphy CT.  2012.  The Intersection of Aging, Longevity Pathways, and Learning and Memory in C. elegans.. Front Genet. 3:259.
Heimbucher T, Murphy CT.  2019.  Investigating Mechanisms that Control Ubiquitin-Mediated DAF-16/FOXO Protein Turnover.. Methods Mol Biol. 1890:41-49.
Shi C, Runnels AM, Murphy CT.  2017.  Mating and male pheromone kill \textitCaenorhabditis males through distinct mechanisms. eLife. 6:e23493.
Shi C, Murphy CT.  2014.  Mating induces shrinking and death in Caenorhabditis mothers.. Science. 343(6170):536-40.
Shi C, Runnels AM, Murphy CT.  2016.  Mating-induced Male Death and Pheromone Toxin-regulated Androstasis. bioRxiv.
Li S, Stone HA, Murphy CT.  2015.  A microfluidic device and automatic counting system for the study of C. elegans reproductive aging.. Lab Chip. 15(2):524-31.
Murphy CT, Rock RS, Spudich JA.  2001.  A myosin II mutation uncouples ATPase activity from motility and shortens step size.. Nat Cell Biol. 3(3):311-5.
Mack HID, Heimbucher T, Murphy C.T..  2019.  The nematode Caenorhabditis elegans as a model for aging research. Drug Discov Today: Disease Models .
Arey RN, Kaletsky R., Murphy CT.  2019.  Nervous system-wide profiling of presynaptic mRNAs reveals regulators of associative memory. Sci Rep, . 9
Li L-B, Lei H, Arey RN, Li P, Liu J, Murphy CT, Xu XZShawn, Shen K.  2016.  The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory.. Curr Biol. 26(5):605-15.
Caudy AA, Guan Y, Jia Y, Hansen C, DeSevo C, Hayes AP, Agee J, Alvarez-Dominguez JR, Arellano H, Barrett D et al..  2013.  A new system for comparative functional genomics of Saccharomyces yeasts.. Genetics. 195(1):275-87.