Publications Search

95 Publications


Caudy A, Guan Y, Jia Y, Hansen C, DeSevo C, Hayes A, Agee J, Alvarez-Dominguez J, Arellano H, Barrett D, et al. 2013. A new system for comparative functional genomics of Saccharomyces yeasts. Genetics. 195(1):275-87. doi:10.1534/genetics.113.152918.


Heimbucher T, Murphy CT. 2019. A PBX/MEIS Complex Balances Reproduction and Somatic Resilience. Developmental Cell. 49(2).
Moore R, Kaletsky R, Murphy C. 2019. Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance. Cell. 177(7): - 1841.e12.
Tepper R, Ashraf J, Kaletsky R, Kleemann G, Murphy C, Bussemaker H. 2013. PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity. Cell. 154(3):676-690. doi:10.1016/j.cell.2013.07.006.
Heimbucher T, Hog J, Murphy CT. 2019. PQM-1 controls hypoxic survival via regulation of lipid metabolism. bioRxiv.
Arey R, Kaletsky R, Murphy C. 2019. Profiling of presynaptic mRNAs reveals a role for axonal PUMILIOs in associative memory formation. bioRxiv.. doi:10.1101/733428.


Hsu A-L, Murphy C, Kenyon C. 2003. Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science. 300(5622):1142-5. doi:10.1126/science.1083701.
Templeman N, Murphy C. 2018. Regulation of reproduction and longevity by nutrient-sensing pathways. The Journal of Cell Biology. 217:93–106. doi:10.1083/jcb.201707168.
Son H, Seo M, Ham S, Hwang W, Lee D, An S, Artan M, Seo K, Kaletsky R, Arey R, et al. 2017. RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans. Nat Commun. 8:14749. doi:10.1038/ncomms14749.
Kaletsky R, Murphy C. 2010. The role of insulin/IGF-like signaling in C. elegans longevity and aging. Dis Model Mech. 3(7-8):415-9. doi:10.1242/dmm.001040.


Murphy C. 2006. The search for DAF-16/FOXO transcriptional targets: approaches and discoveries. Exp Gerontol. 41(10):910-21. doi:10.1016/j.exger.2006.06.040.
Murphy C, Spudich J. 1999. The sequence of the myosin 50-20K loop affects Myosin's affinity for actin throughout the actin-myosin ATPase cycle and its maximum ATPase activity. Biochemistry. 38(12):3785-92. doi:10.1021/bi9826815.
Maliha G, Murphy C. 2016. A simple offspring-to-mother size ratio predicts post-reproductive lifespan. bioRxiv.. doi:10.1101/048835.


Luo S, Shaw W, Ashraf J, Murphy C. 2009. TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging. PLoS Genet. 5(12):e1000789. doi:10.1371/journal.pgen.1000789.
Luo S, Kleemann G, Ashraf J, Shaw W, Murphy C. 2010. TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance. Cell. 143(2):299-312. doi:10.1016/j.cell.2010.09.013.
Murphy C, Lee S-J, Kenyon C. 2007. Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans. Proc Natl Acad Sci U S A. 104(48):19046-50. doi:10.1073/pnas.0709613104.
Kaletsky R, Yao V, Williams A, Runnels A, Tadych A, Zhou S, Troyanskaya O, Murphy C. 2018. Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression. PLoS Genet. 14(8):e1007559. doi:10.1371/journal.pgen.1007559.


Murphy C. 2006. Using whole-genome transcriptional analyses to identify molecular mechanisms of aging. Drug Discovery Today: Disease Mechanisms. 3:41 - 46. doi:


Murphy C, Spudich J. 2000. Variable surface loops and myosin activity: accessories to a motor. J Muscle Res Cell Motil. 21(2):139-51.


Lakhina V, McReynolds M, Grimes D, Rabinowitz J, Burdine R, Murphy C. 2019. ZIP-5/bZIP transcription factor regulation of folate metabolism is critical for aging axon regeneration. bioRxiv.:727719.