Publications Search

Found 95 results
Author Keyword Title Type [ Year(Asc)]
2010
Landis JN, Murphy CT.  2010.  Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO.. Dev Dyn. 239(5):1405-12.
Kaletsky R, Murphy CT.  2010.  The role of insulin/IGF-like signaling in C. elegans longevity and aging.. Dis Model Mech. 3(7-8):415-9.
Luo S, Kleemann GA, Ashraf JM, Shaw WM, Murphy CT.  2010.  TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance.. Cell. 143(2):299-312.
2009
Oliveira RP, Abate JPorter, Dilks K, Landis J, Ashraf J, Murphy CT, T Blackwell K.  2009.  Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf.. Aging Cell. 8(5):524-41.
Kleemann GA, Murphy CT.  2009.  The endocrine regulation of aging in Caenorhabditis elegans.. Mol Cell Endocrinol. 299(1):51-7.
Chikina MD, Huttenhower C, Murphy CT, Troyanskaya OG.  2009.  Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans.. PLoS Comput Biol. 5(6):e1000417.
Lee S-J, Murphy CT, Kenyon C.  2009.  Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.. Cell Metab. 10(5):379-91.
Luo S, Shaw WM, Ashraf J, Murphy CT.  2009.  TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging.. PLoS Genet. 5(12):e1000789.
2007
Shaw WM, Luo S, Landis J, Ashraf J, Murphy CT.  2007.  The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling.. Curr Biol. 17(19):1635-45.
Murphy CT, Lee S-J, Kenyon C.  2007.  Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans.. Proc Natl Acad Sci U S A. 104(48):19046-50.
2006
Kenyon C, Murphy CT.  2006.  Enrichment of regulatory motifs upstream of predicted DAF-16 targets.. Nat Genet. 38(4):397-8;authorreply398.
Murphy CT.  2006.  The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.. Exp Gerontol. 41(10):910-21.
Murphy CT.  2006.  Using whole-genome transcriptional analyses to identify molecular mechanisms of aging. Drug Discovery Today: Disease Mechanisms. 3:41-46.
2004
McCarroll SA, Murphy CT, Zou S, Pletcher SD, Chin C-S, Jan YNung, Kenyon C, Bargmann CI, Li H.  2004.  Comparing genomic expression patterns across species identifies shared transcriptional profile in aging.. Nat Genet. 36(2):197-204.
2003
Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, Li H, Kenyon C.  2003.  Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans.. Nature. 424(6946):277-83.
Hsu A-L, Murphy CT, Kenyon C.  2003.  Regulation of aging and age-related disease by DAF-16 and heat-shock factor.. Science. 300(5622):1142-5.
2001
Murphy CT, Rock RS, Spudich JA.  2001.  A myosin II mutation uncouples ATPase activity from motility and shortens step size.. Nat Cell Biol. 3(3):311-5.
2000
Murphy CT, Spudich JA.  2000.  Variable surface loops and myosin activity: accessories to a motor.. J Muscle Res Cell Motil. 21(2):139-51.
1999
Murphy CT, Spudich JA.  1999.  The sequence of the myosin 50-20K loop affects Myosin's affinity for actin throughout the actin-myosin ATPase cycle and its maximum ATPase activity.. Biochemistry. 38(12):3785-92.
1998
Murphy CT, Spudich JA.  1998.  Dictyostelium myosin 25-50K loop substitutions specifically affect ADP release rates.. Biochemistry. 37(19):6738-44.

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