Publications Search

Found 94 results
Author Keyword Title [ Type(Asc)] Year
Journal Article
Lakhina V, McReynolds M, Grimes DT, Rabinowitz JD, Burdine RD, Murphy CT.  2019.  ZIP-5/bZIP transcription factor regulation of folate metabolism is critical for aging axon regeneration. bioRxiv. :727719.
Murphy CT, Spudich JA.  2000.  Variable surface loops and myosin activity: accessories to a motor.. J Muscle Res Cell Motil. 21(2):139-51.
Murphy CT.  2006.  Using whole-genome transcriptional analyses to identify molecular mechanisms of aging. Drug Discovery Today: Disease Mechanisms. 3:41-46.
Kaletsky R, Yao V, Williams A, Runnels AM, Tadych A, Zhou S, Troyanskaya OG, Murphy CT.  2018.  Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression.. PLoS Genet. 14(8):e1007559.
Murphy CT, Lee S-J, Kenyon C.  2007.  Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans.. Proc Natl Acad Sci U S A. 104(48):19046-50.
Luo S, Kleemann GA, Ashraf JM, Shaw WM, Murphy CT.  2010.  TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance.. Cell. 143(2):299-312.
Luo S, Shaw WM, Ashraf J, Murphy CT.  2009.  TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging.. PLoS Genet. 5(12):e1000789.
Maliha G, Murphy CT.  2016.  A simple offspring-to-mother size ratio predicts post-reproductive lifespan. bioRxiv.
Murphy CT, Spudich JA.  1999.  The sequence of the myosin 50-20K loop affects Myosin's affinity for actin throughout the actin-myosin ATPase cycle and its maximum ATPase activity.. Biochemistry. 38(12):3785-92.
Murphy CT.  2006.  The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.. Exp Gerontol. 41(10):910-21.
Kaletsky R, Murphy CT.  2010.  The role of insulin/IGF-like signaling in C. elegans longevity and aging.. Dis Model Mech. 3(7-8):415-9.
Son HG, Seo M, Ham S, Hwang W, Lee D, An SWoo A, Artan M, Seo K, Kaletsky R, Arey RN et al..  2017.  RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans.. Nat Commun. 8:14749.
Templeman NM, Murphy CT.  2018.  Regulation of reproduction and longevity by nutrient-sensing pathways. The Journal of Cell Biology. 217:93–106.
Hsu A-L, Murphy CT, Kenyon C.  2003.  Regulation of aging and age-related disease by DAF-16 and heat-shock factor.. Science. 300(5622):1142-5.
Arey R, Kaletsky R, Murphy CT.  2019.  Profiling of presynaptic mRNAs reveals a role for axonal PUMILIOs in associative memory formation. bioRxiv.
Heimbucher T, Hog J, Murphy CT.  2019.  PQM-1 controls hypoxic survival via regulation of lipid metabolism. bioRxiv.
Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, Bussemaker HJ.  2013.  PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity.. Cell. 154(3):676-690.
Moore RS, Kaletsky R, Murphy CT.  2019.  Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance. Cell. 177(7):-1841.e12.
Heimbucher T, Murphy CT.  2019.  A PBX/MEIS Complex Balances Reproduction and Somatic Resilience. Developmental Cell. 49(2)
Caudy AA, Guan Y, Jia Y, Hansen C, DeSevo C, Hayes AP, Agee J, Alvarez-Dominguez JR, Arellano H, Barrett D et al..  2013.  A new system for comparative functional genomics of Saccharomyces yeasts.. Genetics. 195(1):275-87.
Li L-B, Lei H, Arey RN, Li P, Liu J, Murphy CT, Xu XZShawn, Shen K.  2016.  The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory.. Curr Biol. 26(5):605-15.
Arey RN, Kaletsky R., Murphy CT.  2019.  Nervous system-wide profiling of presynaptic mRNAs reveals regulators of associative memory. Sci Rep, . 9
Mack HID, Heimbucher T, Murphy C.T..  2019.  The nematode Caenorhabditis elegans as a model for aging research. Drug Discov Today: Disease Models .
Murphy CT, Rock RS, Spudich JA.  2001.  A myosin II mutation uncouples ATPase activity from motility and shortens step size.. Nat Cell Biol. 3(3):311-5.
Li S, Stone HA, Murphy CT.  2015.  A microfluidic device and automatic counting system for the study of C. elegans reproductive aging.. Lab Chip. 15(2):524-31.

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